the apothecarium las vegas a medical and legal adult use marijuana dispensary discuss cbc or cannabichromene a cannabinoid found in the cannabis plant

What are cannabinoids?

Cannabinoids are the naturally occurring chemical compounds found in the cannabis plant. Cannabinoids are partly responsible for the wide array of medicinal and psychoactive effects cannabis may provide. Currently there are over 110 known cannabinoids with more likely to be discovered as studies continue to reveal the complex molecular structures of the cannabis plant.

Cannabinoids interact with human physiology through the endocannabinoid system (ECS), the set of receptors that function to regulate health and promote homeostasis throughout the body. The ECS has two primary receptors, the CB1 and CB2. The CB1 receptor binds primarily to the brain and nervous system, while the CB2 receptor interacts largely with the immune system. The cannabis plant relies on cannabinoids binding to these receptors to produce the array of potential benefits and effects. Each cannabinoid holds unique characteristics of their own that are worth noting in order to maximize desired effects from medicating with cannabis.

What is CBC?

Cannabichromene (CBC) is a non-psychoactive cannabinoid with a host of potential therapeutic applications. CBC may carry pain relieving properties, act as a potent anti-inflammatory agent, assist with digestive and gastrointestinal disorders, possess antibacterial and antifungal efficacy, and could potentially contribute to the regeneration of brain cells, which possibly has implications in the treatments of multiple sclerosis, fibromyalgia, dementia, Alzheimer’s and other neurodegenerative related conditions.

CBC is typically found in low levels in most cannabis strains and shares molecular similarity to other cannabinoids such as THC and CBD. CBC is also a descendant of CBG, which acts a chemical precursor to these three major cannabinoids. CBC may work most effectively when paired with other cannabinoids and terpenes to maximize the whole plant medicinal spectrum cannabis potentially offers.

How does CBC work?

CBC is widely considered to indirectly bind with the ECS through stimulation of the body’s naturally occurring endocannabinoids, anandamide and 2-AG. CBC may also act as an agonist to the TRPV1 and TRPA1 receptors, which modulate pain sensitivity, body temperature, and neurogenic inflammation. CBC is thought to bind on a minimal level with the CB1 and CB2 receptors but ongoing research may clarify the complexity of this cannabinoid.

CBC displays the potential to deeply influence the benefits and effects of cannabis, particularly with its non-intoxicating properties. CBC could play a major role in cannabis based medicine as a deeper understanding of cannabinoids and the ECS continually evolves. Feel free to ask any of our knowledgeable patient consultants with any questions you may have.

The Research

The antidepressant effects of CBC and other cannabinoids was the focus of a June 2010 study. A November 2010 study evaluated the anti-inflammatory properties of both CBC and THC, with optimal results when taken together. The pain relieving effects of CBC and CBD were examined in a February 2011 study. The potential of CBC to modulate gastrointestinal motility was the subject of a February 2012 study. A November 2013 study suggests CBC may promote neurogenesis, showing promise for a variety of neurodegenerative disorders. CBC could potentially aid in the treatment of acne and other skin conditions according to a September 2016 study.

References:

http://norml.org/library/item/introduction-to-the-endocannabinoid-system

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3417484/

https://www.ncbi.nlm.nih.gov/pubmed/20332000

https://www.ncbi.nlm.nih.gov/pubmed/20619971

https://www.ncbi.nlm.nih.gov/pubmed/20942863

https://bpspubs.onlinelibrary.wiley.com/doi/abs/10.1111/j.1476-5381.2012.01879.x

https://www.ncbi.nlm.nih.gov/pubmed/27094344

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